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KMID : 0359320220620040008
Korean Journal of Veterinary Research
2022 Volume.62 No. 4 p.8 ~ p.8
Feline progressive histiocytosis in four cats: case reports
Kim Ji-Su

Yim So-Jeong
Kim Jae-Hoon
Jung Ji-Youl
Abstract
We describe four cases of feline progressive histiocytosis (FPH) including three females (one intact, two spayed) and one castrated male cat, with a mean age of 5.95 years at diagnosis. Masses were found under the skin of head, lip, neck, and vulva. Histologically, proliferative round cells had ovoid nuclei, foamy eosinophilic cytoplasm, distinct cytoplasmic processes, and numerous mitotic figures. Immunohistochemically, all cases were positive for Iba1 and MHC II (Dako). One case showed cytoplasmic positive staining for E-cadherin. To the best of our knowledge, this is the first documented report of FPH in Korea.
KEYWORD
cats, histiocytosis, immunohistochemistry, skin
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